Parts Used: Dried Inner Bark
16 Quinones containing both naphthoquinones: (lapachol 2-7% [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphtalene-dione], menaquinone-I, deoxylapachol, beta-lapachone, alpha-lapachone and dehydro-alpha-lapachone) and anthraquinones: (2-methylanthraquinone, 2 hydroxymenthylanthraquinone, 2-acetoxymethylanthraquinone, anthraquinone-2-aldehyde, 1-hydroxyanthraquinone, 1-methoxyanthraquinone, 2-hydroxy-3-methylquinone and tabebulin).
Thought to be very rare to have both these groups of quinones occurring in the same plant, seeveral of the remarkable properties of pau d’arco may be due to a probable synergy between naphthoquinones and anthraquinones.
The additional 38constituents include tabebuin, lapachenole, quercetin, o- and p-hydroxybenzoic acids, benzaldehyde derivatives, cyclopentene dialdehyde, flavonoids, iridoid glycosides, lignan glycosides, isocoumarin glycosides, phenylethanoid glycosides and phenolic glycosides
Major Safety Issues:
Do not use during pregnancy or lactation. Avoid in those who are taking anticoagulant, or antiplatelet medications or supplements, as it may increase the risk of bleeding. The ability for it to interact with other medicines administered at the same time, particularly those with similar or opposing effects, should be taken into consideration.